Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, caused by progressive loss of motor neurons.Changes are widespread in the subcortical white matter in ALS.Diffusion tensor imaging (DTI) detects pathological changes in white matter fibres in vivo, based on alterations in the degree (diffusivity, ADC) and
Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Abstract The highly mutated and transmissible Omicron (BA.1) and its more contagious lineage BA.2 have provoked serious concerns over their decreased sensitivity to the current COVID-19 vaccines and evasion from most anti-SARS-CoV-2 neutralizing antibodies (NAbs).In this study, we explored the possibility of combating the Omicron and BA.2 by constr
Peculiarities of the course of bronchopulmonary dysplasia associated with microaspiration of gastric contents
Tracheobronchial aspirate (TBA) was tested for marker of micro-aspiration john boos countertop board of gastric contents - pepsin followed by analysis of the incidence and clinical picture of the developed bronchopulmonary dysplasia (BPD) in patients with and without microaspiration.Found that in children with micro-aspiration the frequency and the